 | 2021-07-27 8:00 PM | WAS - Tyrone Swoopes (TE) | Undisclosed | [CBS] Did Not Report |
| 2021-07-27 8:00 PM | WAS - Najee Toran (OG) | Undisclosed | [CBS] Did Not Report |
| 2021-07-27 8:00 PM | LAC - John Hurst (WR) | Undisclosed | [CBS] Physically Unable to Perform. Expected Return - Week 2 |
| 2021-07-27 8:00 PM | KC - Nick Keizer (TE) | Undisclosed | [CBS] Active/NFI |
| 2021-07-27 8:00 PM | KC - Kyle Long (OG) | Knee | [CBS] Physically Unable to Perform. Expected Return - Week 2 |
| 2021-07-27 8:00 PM | HOU - Pharaoh Brown (TE) | Undisclosed | [CBS] Active/NFI |
| 2021-07-27 8:00 PM | HOU - Lonnie Johnson (CB) | Undisclosed | [CBS] Active/NFI |
| 2021-07-27 8:00 PM | HOU - Cornell Armstrong (DB) | Undisclosed | [CBS] Active/NFI |
| 2021-07-27 8:00 PM | HOU - DeMarcus Walker (DE) | Undisclosed | [CBS] Active/NFI |
| 2021-07-27 8:00 PM | GB - Henry Black (SAF) | Undisclosed | [CBS] Active/NFI |
| 2021-07-27 8:00 PM | GB - Kevin King (CB) | Undisclosed | [CBS] Active/NFI |
| 2021-07-27 8:00 PM | GB - Kingsley Keke (DT) | Undisclosed | [CBS] Active/NFI |
| 2021-07-27 8:00 PM | GB - Will Redmond (CB) | Undisclosed | [CBS] Active/NFI |
| 2021-07-27 8:00 PM | GB - Tipa Galeai (LB) | Undisclosed | [CBS] Active/NFI |
| 2021-07-27 8:00 PM | CAR - Lano Hill (DB) | Undisclosed | [CBS] Physically Unable to Perform. Expected Return - Week 2 |
| 2021-07-27 7:30 PM | KC - Chris Finke (WR) | Undisclosed | [CBS] IR. Injured Reserve. Expected Return - Week 4 |
| 2021-07-27 7:30 PM | HOU - Buddy Howell (RB) | Undisclosed | [CBS] IR. Reserve - COVID-19 |
| 2021-07-27 7:30 PM | HOU - Geron Christian (OT) | Undisclosed | [CBS] IR. Reserve - COVID-19 |
| 2021-07-27 7:30 PM | DAL - Mitch Hyatt (OT) | Knee | [CBS] IR. Injured Reserve. Expected Return - Week 4 |
| 2021-07-27 7:30 PM | CAR - Frankie Luvu (LB) | Undisclosed | [CBS] IR. Reserve - COVID-19 |