 | 2022-09-28 10:40 PM | TOR - Jordie Benn (D) | Groin | [CBS] Questionable for start of season |
| 2022-09-28 10:40 PM | TOR - Carl Dahlstrom (D) | Shoulder | [CBS] Questionable for start of season |
| 2022-09-28 9:10 PM | EDM - Vincent Desharnais (D) | Wrist | [USA] out: Desharnais is expected to be idle until at least the end of October after undergoing wrist surgery.. |
| 2022-09-28 8:40 PM | TOR - Carl Dahlstrom (D) | Undisclosed | [CBS] Questionable for start of season |
| 2022-09-28 8:10 PM | TOR - Jordie Benn (D) | Undisclosed | [CBS] Questionable for start of season |
| 2022-09-28 4:40 PM | SJS - Oskar Lindblom (LW) | Upper Body | [CBS] Questionable for start of season |
| 2022-09-28 4:10 PM | ANA - Max Jones (LW) | Lower Body | [CBS] Questionable for start of season |
| 2022-09-28 3:10 PM | PIT - Teddy Blueger (C) | Upper Body | [CBS] Questionable for start of season |
| 2022-09-28 2:10 AM | ANA - Max Jones (LW) | Undisclosed | [CBS] Questionable for start of season |
| 2022-09-27 10:10 PM | STL - Scott Perunovich (D) | Upper Body | [CBS] Questionable for start of season |
| 2022-09-27 8:10 PM | VAN - Ilya Mikheyev (RW) | Lower Body | [USA] questionable: Mikheyev is battling a lower-body injury, and it is unclear if he will face the Oilers on October 12.. |
| 2022-09-27 4:40 PM | VAN - Ilya Mikheyev (RW) | Lower Body | [CBS] Questionable for start of season |
| 2022-09-27 4:10 PM | TOR - John Tavares (C) | Oblique | [CBS] Expected to be out until at least Oct 20 |
| 2022-09-27 2:40 PM | TOR - John Tavares (C) | Oblique | [USA] out: Tavares is out of commission due to an oblique strain, and he will miss at least three weeks of action.. |
| 2022-09-27 2:40 PM | VAN - Travis Dermott (D) | Undisclosed | [CBS] Questionable for start of season |
| 2022-09-27 1:40 PM | STL - Martin Frk (RW) | Lower Body | [CBS] Questionable for start of season |
| 2022-09-27 12:40 PM | PIT - Kasperi Kapanen (RW) | Illness | [CBS] Questionable for start of season |
| 2022-09-27 12:40 PM | DET - Jakub Vrana (LW) | Illness | [CBS] Questionable for start of season |
| 2022-09-27 10:10 AM | TOR - John Tavares (C) | Upper Body | [CBS] Questionable for start of season |
| 2022-09-26 9:40 PM | VAN - Brock Boeser (RW) | Hand | [USA] out: Boeser is recovering from hand surgery, and he is projected to miss three to four weeks.. |